High Prevalence of the ACSL (rs6552828) AA Genotype among Elite Soccer Players

Background: The ACSL A/G single nucleotide polymorphism is associated with endurance trainability. It was previously demonstrated that AA carriers had a reduced maximal oxygen consumption (VO2 max) in response to training compared GG carriers, and this explained 6.1% of the variance VO2 max training. aim present study determine prevalence among soccer players. Methods: One hundred sixty-seven male athletes (60 players, 48 sprinters jumpers, 59 long distance runners) 60 non-athletic controls participated study. Genomic DNA extracted from buccal epithelial cells using standard protocol for genotyping. Results: genotype significantly higher players (35%) (12%), jumpers (15%) long-distance runners (15%). findings suggest despite importance aerobic capacity performance, – related trainability power controls. This genetically unfavorable predisposition should be considered when selecting team squad planning fitness modalities throughout competitive season. Keywords: sprinters, runners, genetic polymorphism.